Correct, the MAOI's are the things to look out for. Smoking DMT will not have these adverse effects (i.e. hypertension). Monoamine oxidase is necessary for the metabolism of many things, notably certain neurotransmitters like serotonin, dopamine, & norepinephrine. When MAO is inhibited, garbage can build up. This isn't so bad by itself, if you're fasting. But you can run into trouble if you ingest foods containing Tyramine (cheese, red wine, anything aged). With MAO inhibited, the Tyramine does not get metabolised. Basically, more Tyramine equals more norepinephrine, and more norepinephrine equals a hypertensive crisis (think "fight or flight" - higher heart rate and blood pressure). The results can be a severe headache or even death.
This is also why you don't mix MAOI's with amphetamines or amphetamine derivatives like MDMA. You're adding hypertension on top of a drug that is already amping your system. Bad idea.
If you're going to use MAOI's, I suggest following these tips:
1. Fast for the whole day. Only break the fast on water, juice, breads, & nuts.
2. Do not mix MAOI's with amphetamines or analogues like MDMA
3. They work best when mixed with tryptamines (DMT, Psilocybin) or indoles (LSD & it's analogues).
(From Erowid)
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